Can The Regular Use Of THC-O Result In Weight Gain? - Algia Medical

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Can The Regular Use Of THC-O Result In Weight Gain?

by Ethan More

After the legalization of hemp products, more research has been conducted on the hemp plant. It carries over 113 cannabinoids, each with unique effects. The gaining popularity of cannabis led the manufacturer to bring in THC-O. It is a synthetic compound derived from the hemp plant. It is new to the industry, and people should know the potential effects.

THC or tetrahydrocannabinol is a well-known active ingredient in marijuana that produces high. It consists of many therapeutic properties. THC-O acetate is a new version of cannabinoid and an analog of THC. It is three times more potent than other cannabinoids in nature. It gives more spiritual, relaxing effects and people use it for weight and appetite management.

What is THC-O?

Hemp contains less amount of THC, which is federally legal by the Farm Bill in 2018. It is also known as THC-O acetate, ATCH, and THC acetate, a synthetic cannabinoid produced from hemp extract. The highly flammable molecule called acetic anhydride was added to manufacture tetrahydrocannabinol-O-acetate. It is carried out through a series of extraction procedures using hemp.

The first step is to extract CBD or cannabidiol from the raw hemp and produce Delta-8 THC. To this, acetic anhydride is added to make THC-O acetate. The manufacture of THC-O is dangerous, and it is not safe to prepare it in your home because the chemicals are highly explosive and flammable. 

ATHC is a pro-drug, and it will be active only after being metabolized by the liver. It is three times more potent than tetrahydrocannabinol. It should be manufactured only in the lab where you need the special equipment and a piece of knowledge about the chemicals. After the metabolization, the leftover compound is the delta-9 THC.ATHC is highly bioavailable than the non-acetylated version. The functional group –O, is removed after the absorption.

How does THC-O work?

THC-O is an acetate version, and it acts on an endocannabinoid system similar to that of other cannabinoids. It will interact strongly with the endocannabinoid system present in our body strongly. Then it goes and binds to the cannabinoid receptors called CB1 and CB 2. It results in the formation of biological responses.

The endocannabinoid system maintains homeostasis and makes you feel better than before. Binding to the receptor involved in controlling mood swings normalizes sleep patterns, reduces stress levels, boosts the immune system, prevents pain sensation, etc. All this may affect balancing the weight.

THC-O acetate binds to the CB 1 receptor and activates the receptor to release the hormone and increase your appetite. Binding to the CB 2 receptor results in the antagonist action, inhibits the receptor and reduces food cravings and hunger. The potency of the THC-O acetate is not the same for all people, and it varies from one individual to another.

Can the regular use of THC-O result in weight gain?

1. Effect on the energy level

Consuming tetrahydrocannabinol-O-acetate interacts with the neural receptors present in the brain and boosts the energy level. It makes you physically active. It makes the burning of extra calories in your body and increases your appetite, and balances the weight.

2. Effect on digestion

A healthy digestive system helps manage the balance of weight gain and weight loss. Indigestion is one of the reasons for the loss of weight that causes uneasiness and pain in the bowel. It is treated with cannabinoids and increases your appetite.

3. Effect on the sleep-wake cycle

The synthetic cannabinoid THC-O acetate exhibits an effect on the sleep-wake cycle. Lack of sleep results in metabolic complications, and there will be an alteration in weight. Intake of this synthetic cannabinoid acts as a quick defense against the irregular sleep cycle and will allow a good sleep to maintain a healthy lifestyle with good mental health. 

Is THC-O acetate legal?

The Farm Bill in 2018 declared that all the products produced from the hemp plants are federally legal, which consists of less than 0.3% of tetrahydrocannabinol or THC. It is a popular and legal hemp product that came into existence in the market.

Things to consider before taking ATHC

Delta 8 Vape Pen + D9 + D10 + Thc-O - Lemon Jack - Sativa 2G

ATHC is produced synthetically in the laboratory by using highly flammable chemicals. Consult with your physician before taking any THC-O acetate products in your diet. They will examine your health and recommend the dosage level. You should consider the following things when using synthetic cannabinoids.

1. Intake methods

You can take this ATHC in many ways, like that of marijuana and other cannabinoids. It has several medicinal benefits such as reducing stress, stimulating appetite, removing anxiety, preventing nausea, reducing pain, etc. You can consume it by smoking, vaping, oral administration, topical, or sublingual. Also, it can increase your mood and promotes focus and concentration. It is best to consume orally or by vaping. 

2. Rate of absorption

In the acetate form, it takes about 20 to 30 minutes to get an effect. After the intake, the de-acetylation process occurs by enzymes present in our system. It becomes active and results in psychoactive effects. The fastest delivery method is through tinctures rather than the edibles. Keeping a drop of medicine beneath the tongue gets absorbed and reaches the bloodstream. 

3. Start slow

The beginners of cannabis should start with a small dose first, and then depending upon the experience; you should increase the dosage gradually. Overdose may increase your psychoactive effects, so you have to consult with your doctor about your dosage level to get rid of these effects. 

4. High-quality products

It is a crucial factor to consider when consuming it. It is already highly potent and delivers the action quickly. So, do not go for the cheap quality of the products. Please buy it from genuine and trusted vendors. They will always sell high-quality and legal hemp products only. Ensure the legal status in your area before purchasing it.

5. Side-effects

ATHC is potent, and it may result in undesirable side effects such as lethargy, drowsiness, vomiting, nausea, etc. 

Is ATHC safe to consume?

It is safe to drink. You should take care when you buy or consume this product. It will not offer any harmful effects when taken in a large dose.


ATHC has many therapeutic properties, and the effect may vary from one person to another in case of weight loss and weight gain. It may interact with any other prescriptions and gives you adverse effects.

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